Therapeutic potential of a novel semi-synthetic-sulfated-polysaccharide to suppress inflammatory mediators in P. gingivalis LPS stimulated human monocytes/macrophages
Abstract Background Chronic periodontitis is associated with an increased risk for systemic conditions such as cardiovascular disease, diabetes, and osteoporosis. During chronic periodontitis, endotoxin (lipopolysaccharide, LPS) produced by P. gingivalis provokes monocyte accumulation and differenti...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
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Series: | Journal of Inflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12950-021-00292-6 |