What makes ribosome-mediated transcriptional attenuation sensitive to amino acid limitation?

Ribosome-mediated transcriptional attenuation mechanisms are commonly used to control amino acid biosynthetic operons in bacteria. The mRNA leader of such an operon contains an open reading frame with "regulatory" codons, cognate to the amino acid that is synthesized by the enzymes encoded...

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Bibliographic Details
Main Authors: Johan Elf, Måns Ehrenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0010002