Diastereoselective synthesis and anticancer potential of a small library of cage-like heterocyclic hybrids

Diastereoselective synthesis and anticancer potential of a small library of cage-like heterocyclic hybrids

With an aim to construct novel anticancer drugs, a series of polycyclic heterocycles comprising diverse structural sub-units based on molecular hybridization strategy have been designed and synthesized through a three-component [3 + 2]-cycloaddition/annulation strategy. Anticancer evaluation of thes...

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Bibliographic Details
Main Authors: Raju Suresh Kumar, Abdulrahman I. Almansour, Natarajan Arumugam, Kotresha D, Janardhana Papayya Balakrishna
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of King Saud University: Science
Subjects:
Cage-like heterocyclic hybrids
Stereoselective synthesis
MCF-7
Flow cytometry
Apoptosis
JC1
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364720303529

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http://www.sciencedirect.com/science/article/pii/S1018364720303529

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