Synthesis and Antithrombotic Activity Determination of (2-Methyl-4-[4-methyl-2-(4-trifluoromethylphenyl)-thiazole-5-ylmethylsulfanyl]phenoxy)acetic Acid Derivatives

Synthesis and Antithrombotic Activity Determination of (2-Methyl-4-[4-methyl-2-(4-trifluoromethylphenyl)-thiazole-5-ylmethylsulfanyl]phenoxy)acetic Acid Derivatives

The article proposes an approach for obtaining the derivatives of hetarylmethylthioaryloxyalcane PPARS/fi agonists containing sulfoxide and sulfone fragments in the linker, the parent compound for the synthesis being GSK-516 - (2-methyl-4-[4-methyl-2-(4-trifiuoromethylph.enyl)-th.iazole-5-ylmethylsu...

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Bibliographic Details
Main Authors: D. V. Minin, S. V. Popkov, M. L. Burdeyny, V. M. Goncharov, S. V. Vasilevsky
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2019-07-01
Series:Тонкие химические технологии
Subjects:
ppar agonists
antithrombotic activity
aryloxyacetic acid
peroxisome proliferation receptors
thiazoles
gsk-516
ppar6/fi
Online Access:https://www.finechem-mirea.ru/jour/article/view/1273

Internet

https://www.finechem-mirea.ru/jour/article/view/1273

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