Adoptive cell therapy using PD-1+ myeloma-reactive T cells eliminates established myeloma in mice

Adoptive cell therapy using PD-1+ myeloma-reactive T cells eliminates established myeloma in mice

Abstract Background Adoptive cellular therapy (ACT) with cancer antigen-reactive T cells following lymphodepletive pre-conditioning has emerged as a potentially curative therapy for patients with advanced cancers. However, identification and enrichment of appropriate T cell subsets for cancer eradic...

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Bibliographic Details
Main Authors: Weiqing Jing, Jill A. Gershan, Grace C. Blitzer, Katie Palen, James Weber, Laura McOlash, Matthew Riese, Bryon D. Johnson
Format: Article
Language:English
Published: BMJ Publishing Group 2017-06-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Myeloma
Adoptive cell therapy
PD-1
PD-L1
Cancer-infiltrating lymphocytes
Online Access:http://link.springer.com/article/10.1186/s40425-017-0256-z

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http://link.springer.com/article/10.1186/s40425-017-0256-z

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