Tuberculosis Biomarker Extraction and Isothermal Amplification in an Integrated Diagnostic Device.

In this study, we integrated magnetic bead-based sample preparation and isothermal loop mediated amplification (LAMP) of TB in a single tube. Surrogate sputum samples produced by the Program for Appropriate Technology in Health containing inactivated TB bacteria were used to test the diagnostic. In...

Full description

Bibliographic Details
Main Authors: Amy Creecy, Patricia K Russ, Francesca Solinas, David W Wright, Frederick R Haselton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4488445?pdf=render