Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and Steatohepatitis

Liver fat accumulation generally related to systemic insulin resistance characterizes nonalcoholic fatty liver disease (NAFLD), which in the presence of nonalcoholic steatohepatitis (NASH) can progress towards cirrhosis and hepatocellular carcinoma. Due to the epidemic of obesity, NAFLD is now the m...

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Bibliographic Details
Main Authors: Paola Dongiovanni, Stefano Romeo, Luca Valenti
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/460190