Challenging the Existing Model of the Hexameric HIV-1 Gag Lattice and MA Shell Superstructure: Implications for Viral Entry

Challenging the Existing Model of the Hexameric HIV-1 Gag Lattice and MA Shell Superstructure: Implications for Viral Entry

Despite type 1 human immunodeficiency virus (HIV-1) being discovered in the early 1980s, significant knowledge gaps remain in our understanding of the superstructure of the HIV-1 matrix (MA) shell. Current viral assembly models assume that the MA shell originates via recruitment of group-specific an...

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Bibliographic Details
Main Authors: Joy Ramielle L. Santos, Weijie Sun, Tarana A. Mangukia, Eduardo Reyes-Serratos, Marcelo Marcet-Palacios
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
HIV-1
matrix shell
viral entry
hexameric matrix trimers
HIV-1 structure
hosohedron
Online Access:https://www.mdpi.com/1999-4915/13/8/1515

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https://www.mdpi.com/1999-4915/13/8/1515

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