Exosomes derived from miR-301a-3p-overexpressing adipose-derived mesenchymal stem cells reverse hypoxia-induced erectile dysfunction in rat models

Exosomes derived from miR-301a-3p-overexpressing adipose-derived mesenchymal stem cells reverse hypoxia-induced erectile dysfunction in rat models

Abstract Background Erectile dysfunction (ED) has often been observed in patients with obstructive sleep apnea (OSA). Research on adipose-derived mesenchymal stem cell (ADSC)-derived exosomes has shown that they have significant therapeutic effects in many diseases including ED. Methods In this stud...

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Bibliographic Details
Main Authors: Li Liang, Dachao Zheng, Chao Lu, Qinghong Xi, Hua Bao, Wengfeng Li, Yufei Gu, Yuanshen Mao, Bin Xu, Xin Gu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Erectile dysfunction
Chronic intermittent hypoxia
Exosomes
miR-301a-3p
Autophagy
Online Access:https://doi.org/10.1186/s13287-021-02161-8

Internet

https://doi.org/10.1186/s13287-021-02161-8

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