Massively parallel whole genome amplification for single-cell sequencing using droplet microfluidics

Abstract Massively parallel single-cell genome sequencing is required to further understand genetic diversities in complex biological systems. Whole genome amplification (WGA) is the first step for single-cell sequencing, but its throughput and accuracy are insufficient in conventional reaction plat...

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Bibliographic Details
Main Authors: Masahito Hosokawa, Yohei Nishikawa, Masato Kogawa, Haruko Takeyama
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05436-4