The functional convergence of antibiotic resistance in β‐lactamases is not conferred by a simple convergent substitution of amino acid

Abstract Bacterial resistance to antibiotics is a serious medical and public health concern worldwide. Such resistance is conferred by a variety of mechanisms, but the extensive variability in levels of resistance across bacteria is a common finding. Understanding the underlying evolutionary process...

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Bibliographic Details
Main Authors: Vivek Keshri, Kevin Arbuckle, Olivier Chabrol, Jean‐Marc Rolain, Didier Raoult, Pierre Pontarotti
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Evolutionary Applications
Subjects:
Online Access:https://doi.org/10.1111/eva.12835