Anesthetic-sensitive ion channel modulation is associated with a molar water solubility cut-off

Anesthetic-sensitive ion channel modulation is associated with a molar water solubility cut-off

Abstract Background NMDA receptor modulation by hydrocarbons is associated with a molar water solubility cut-off. Low-affinity phenolic modulation of GABAA receptors is also associated with a cut-off, but at much lower molar solubility values. We hypothesized that other anesthetic-sensitive ion chan...

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Bibliographic Details
Main Authors: Robert J. Brosnan, Trung L. Pham
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Pharmacology and Toxicology
Subjects:
Anesthesia
Mechanism
Ion channel
Electrophysiology
Aliphatic
Online Access:http://link.springer.com/article/10.1186/s40360-018-0244-z

Internet

http://link.springer.com/article/10.1186/s40360-018-0244-z

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