Designing custom CRISPR libraries for hypothesis-driven drug target discovery

Designing custom CRISPR libraries for hypothesis-driven drug target discovery

Over the last decade Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) has been developed into a potent molecular biology tool used to rapidly modify genes or their expression in a multitude of ways. In parallel, CRISPR-based screening approaches have been developed as powerful disc...

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Bibliographic Details
Main Authors: Vaishnavi Srinivasan Iyer, Long Jiang, Yunbing Shen, Sanjaykumar V. Boddul, Sudeepta Kumar Panda, Zsolt Kasza, Bernhard Schmierer, Fredrik Wermeling
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020303627

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http://www.sciencedirect.com/science/article/pii/S2001037020303627

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