Early-expressed chemokines predict kidney immunopathology in experimental disseminated Candida albicans infections.
The mouse intravenous challenge model of Candida albicans infection is widely used to determine aspects of host-fungus interaction. We investigated the production of cytokines in the kidneys and spleen of animals up to 48 h after challenge with virulent and attenuated isolates and related these resp...
Main Authors: | Donna M MacCallum, Luis Castillo, Alistair J P Brown, Neil A R Gow, Frank C Odds |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-07-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2712765?pdf=render |
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