Early-expressed chemokines predict kidney immunopathology in experimental disseminated Candida albicans infections.

The mouse intravenous challenge model of Candida albicans infection is widely used to determine aspects of host-fungus interaction. We investigated the production of cytokines in the kidneys and spleen of animals up to 48 h after challenge with virulent and attenuated isolates and related these resp...

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Bibliographic Details
Main Authors: Donna M MacCallum, Luis Castillo, Alistair J P Brown, Neil A R Gow, Frank C Odds
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2712765?pdf=render