Inhibition of hTERT Gene Expression by Silibinin-Loaded PLGA-PEG-Fe3O4 in T47D Breast Cancer Cell Line

Inhibition of hTERT Gene Expression by Silibinin-Loaded PLGA-PEG-Fe3O4 in T47D Breast Cancer Cell Line

Introduction: Nowadays, using drug delivery is an essential method to improve cancer therapy through decreasing drug toxicity and increasing efficiency of treatment. Silibinin (C25H22O10), a polyphenolic flavonoid which is isolated from the milk thistle plant, has various applications in cancer ther...

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Bibliographic Details
Main Authors: Zohreh Ebrahimnezhad, Nosratollah Zarghami, Manoutchehr Keyhani, Soumaye Amirsaadat, Abolfazl Akbarzadeh, Mohammad Rahmati, Zohreh Mohammad Taheri, Kazem Nejati-Koshki
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2013-05-01
Series:BioImpacts
Subjects:
Telomerase
Breast cancer
Silibinin
Nano drug
Real-Time PCR
MTT assay
Online Access:http://dx.doi.org/10.5681/bi.2013.005

Internet

http://dx.doi.org/10.5681/bi.2013.005

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