Analysis of peptide-SLA binding by establishing immortalized porcine alveolar macrophage cells with different SLA class II haplotypes

Abstract Primary porcine alveolar macrophages (PAM) are useful for studying viral infections and immune response in pigs; however, long-term use of these cells is limited by the cells’ short lifespan. We immortalized primary PAMs by transfecting them with both hTERT and SV40LT and established two im...

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Bibliographic Details
Main Authors: Quy Van Chanh Le, Thong Minh Le, Hye-Sun Cho, Won-Il Kim, Kwonho Hong, Hyuk Song, Jin-Hoi Kim, Chankyu Park
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-018-0590-2