Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells.

MSCs are widely applied to regenerate heart tissue in myocardial diseases but when grown in standard two-dimensional (2D) cultures exhibit limited potential for cardiac repair and develop fibrogenic features with increasing culture time. MSCs can undergo partial cardiomyogenic differentiation, which...

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Bibliographic Details
Main Authors: Iran Rashedi, Nilesh Talele, Xing-Hua Wang, Boris Hinz, Milica Radisic, Armand Keating
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5663483?pdf=render