Sitaxsentan-Induced Acute Severe Hepatitis Treated with Glucocorticoid Therapy

Endothelin receptor antagonists are commonly used in the treatment of pulmonary hypertension. Sitaxsentan, a selective endothelin A receptor blocker, induces a mild transaminitis in approximately 3% to 5% of patients, but rarely an acute severe hepatitis. A case involving a 61-year-old female with s...

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Bibliographic Details
Main Authors: Marcus W Chin, Robert D Levy, Eric M Yoshida, Michael F Byrne
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2012/567024