A Novel Laccase with Potent Antiproliferative and HIV-1 Reverse Transcriptase Inhibitory Activities from Mycelia of Mushroom Coprinus comatus

A novel laccase was isolated and purified from fermentation mycelia of mushroom Coprinus comatus with an isolation procedure including three ion-exchange chromatography steps on DEAE-cellulose, CM-cellulose, and Q-Sepharose and one gel-filtration step by fast protein liquid chromatography on Superde...

Full description

Bibliographic Details
Main Authors: Shuang Zhao, Cheng-Bo Rong, Chang Kong, Yu Liu, Feng Xu, Qian-Jiang Miao, Shou-Xian Wang, He-Xiang Wang, Guo-Qing Zhang
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/417461