Development of a novel, single-cycle replicable rift valley Fever vaccine.

Rift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) is an arbovirus that causes severe disease in humans and livestock in sub-Saharan African countries. Although the MP-12 strain of RVFV is a live attenuated vaccine candidate, neuroinvasiveness and neurovirulence of MP-12 in mice...

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Bibliographic Details
Main Authors: Shin Murakami, Kaori Terasaki, Sydney I Ramirez, John C Morrill, Shinji Makino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3961198?pdf=render