Ultra-sensitive and rapid detection of nucleic acids and microorganisms in body fluids using single-molecule tethering

Culture-based diagnostic methods for microorganism detection are time-consuming but still the gold standard for conditions such as sepsis. Here the authors present an amplification and purification-free method to detect microorganisms in bodily fluids with high sensitivity: Single MOLecule Tethering...

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Bibliographic Details
Main Authors: Wen-Chih Cheng, Troy Horn, Maya Zayats, Georges Rizk, Samuel Major, Hongying Zhu, Joseph Russell, Zhiguang Xu, Richard E. Rothman, Alfredo Celedon
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18574-7