Connecting lysosomes and mitochondria – a novel role for lipid metabolism in cancer cell death

Connecting lysosomes and mitochondria – a novel role for lipid metabolism in cancer cell death

Abstract Background The understanding of lysosomes has been expanded in recent research way beyond their view as cellular trash can. Lysosomes are pivotal in regulating metabolism, endocytosis and autophagy and are implicated in cancer. Recently it was discovered that the lysosomal V-ATPase, which i...

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Bibliographic Details
Main Authors: Karin Bartel, Helmut Pein, Bastian Popper, Sabine Schmitt, Sudha Janaki-Raman, Almut Schulze, Florian Lengauer, Andreas Koeberle, Oliver Werz, Hans Zischka, Rolf Müller, Angelika M. Vollmar, Karin von Schwarzenberg
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Cell Communication and Signaling
Subjects:
Lysosome
V-ATPase
Mitochondria
Fission
Apoptosis
Lipid metabolism
Online Access:http://link.springer.com/article/10.1186/s12964-019-0399-2

Internet

http://link.springer.com/article/10.1186/s12964-019-0399-2

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