Cardiomyocyte-Specific Circulating Cell-Free Methylated DNA in Esophageal Cancer Patients Treated with Chemoradiation

Cardiomyocyte-Specific Circulating Cell-Free Methylated DNA in Esophageal Cancer Patients Treated with Chemoradiation

Thoracic high-dose radiation therapy (RT) for cancer has been associated with early and late cardiac toxicity. To assess altered rates of cardiomyocyte cell death due to RT we monitored changes in cardiomyocyte-specific, cell-free methylated DNA (cfDNA) shed into the circulation. Eleven patients wit...

Full description

Bibliographic Details
Main Authors: Sarah Martinez Roth, Eveline E. Vietsch, Megan E. Barefoot, Marcel O. Schmidt, Matthew D. Park, Archana Ramesh, Michael R. Lindberg, Giuseppe Giaccone, Anna T. Riegel, Ana Barac, Keith Unger, Anton Wellstein
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Gastrointestinal Disorders
Subjects:
esophageal cancer
therapy response
circulating cell-free DNA
DNA methylation
amplicon sequencing
Online Access:https://www.mdpi.com/2624-5647/3/3/11

Internet

https://www.mdpi.com/2624-5647/3/3/11

Similar Items