Preparation of the active isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase

1-Phenyl-2-decanoylamino-3-morpholino-1-propanol was previously shown to be an effective inhibitor of the glucosyltransferase in liver that forms glucosylceramide. Since the inhibitor consists of four isomers, it was important for further testing to determine which isomer was most effective and to d...

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Bibliographic Details
Main Authors: J Inokuchi, N S Radin
Format: Article
Language:English
Published: Elsevier 1987-05-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520386739