Iron source preference and regulation of iron uptake in Cryptococcus neoformans.
The level of available iron in the mammalian host is extremely low, and pathogenic microbes must compete with host proteins such as transferrin for iron. Iron regulation of gene expression, including genes encoding iron uptake functions and virulence factors, is critical for the pathogenesis of the...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-02-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2242830?pdf=render |