Cortisol and dehydroepiandrosterone sulfate in patients with schizophrenia spectrum disorders with respect to cognitive performance

Prolonged activation of the hypothalamic-pituitary-adrenal (HPA) axis associated with hypercortisolemia may lead to impairments of cognition in various populations. Dehydroepiandrosterone sulfate (DHEA-S) can protect the hippocampus from the detrimental effects of cortisol. However, this phenomenon...

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Bibliographic Details
Main Authors: Błażej Misiak, Patryk Piotrowski, Magdalena Chęć, Jerzy Samochowiec
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Comprehensive Psychoneuroendocrinology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666497621000151