Evation of High-Mobility Group Box 1 after Clinical Autologous Islet Transplantation and Its Inverse Correlation with Outcomes

A major problem after clinical autologous islet transplantation (AIT) is the difficulty in achieving insulin independence. To follow up on our demonstration in a murine model that high-mobility group box 1 (HMGB1) was released from islets and involved in early loss of transplanted islets, we tested...

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Bibliographic Details
Main Authors: Takeshi Itoh, Shuichi Iwahashi, Mazhar A. Kanak, Masayuki Shimoda, Morihito Takita, Daisuke Chujo, Yoshiko Tamura, Ana M. Rahman, Wen Y. Chung, Nicholas Onaca, P. Toby H. Coates, Ashley R. Dennison, Bashoo Naziruddin, Marlon F. Levy M.D., Shinichi Matsumoto
Format: Article
Language:English
Published: SAGE Publishing 2014-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X658980