Astragalus Inhibits Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelial Cells by Down-Regulating β-Catenin

Background/Aims: The epithelial-to-mesenchymal transition (EMT) of peritoneal mesothelial cells (PMCs) is a crucial event in the induction of peritoneal fibrosis (PF), in which canonical Wnt/β-catenin signaling participates. Smads signaling is reported to interact with β-catenin and synergistically...

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Bibliographic Details
Main Authors: Manshu Yu, Jun Shi, Meixiao Sheng, Kun Gao, Lu Zhang, Li Liu, Yilin Zhu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
EMT
Online Access:https://www.karger.com/Article/FullText/495972