The inactivation of RNase G reduces the Stenotrophomonas maltophilia susceptibility to quinolones by triggering the heat shock response.

The inactivation of RNase G reduces the Stenotrophomonas maltophilia susceptibility to quinolones by triggering the heat shock response.

Quinolone resistance is usually due to mutations in the genes encoding bacterial topoisomerases. However different reports have shown that neither clinical quinolone resistant isolates nor in vitro obtained S. maltophilia mutants present mutations in such genes. The mechanisms so far described cons...

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Bibliographic Details
Main Authors: Alejandra eBernardini, Fernando eCorona, Ricardo eDias, Maria Blanca Sanchez, Jose L Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Microbiology
Subjects:
Stenotrophomonas maltophilia
antibiotic resistance
Quinolone resistance
RNase G
Heat shock.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01068/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01068/full

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