(Z)-5-(2,4-Dihydroxybenzylidene)thiazolidine-2,4-dione Prevents UVB-Induced Melanogenesis and Wrinkle Formation through Suppressing Oxidative Stress in HRM-2 Hairless Mice

(Z)-5-(2,4-Dihydroxybenzylidene)thiazolidine-2,4-dione Prevents UVB-Induced Melanogenesis and Wrinkle Formation through Suppressing Oxidative Stress in HRM-2 Hairless Mice

Background. Uncontrolled melanogenesis and wrinkle formation are an indication of photoaging. Our previous studies demonstrated that (Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione (MHY498) inhibited tyrosinase activity and melanogenesis in vitro. Objective. To examine in vivo effects of MHY4...

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Bibliographic Details
Main Authors: Bonggi Lee, Kyoung Mi Moon, Seong Jin Kim, So Hee Kim, Dae Hyun Kim, Hye Jin An, Ji Won Jeong, Ye Ra Kim, Sujin Son, Min Jo Kim, Ki Wung Chung, Eun Kyeong Lee, Pusoon Chun, Young Mi Ha, Min-Sun Kim, Sang Hyun Mo, Hyung Ryong Moon, Hae Young Chung
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/2761463

Internet

http://dx.doi.org/10.1155/2016/2761463

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