Antibody avidity, persistence, and response to antigen recall: comparison of vaccine adjuvants

Abstract Differences in innate immune ‘imprinting’ between vaccine adjuvants may mediate dissimilar effects on the quantity/quality of persisting adaptive responses. We compared antibody avidity maturation, antibody/memory B cell/CD4+ T cell response durability, and recall responses to non-adjuvante...

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Bibliographic Details
Main Authors: Sonia Budroni, Francesca Buricchi, Andrea Cavallone, Patricia Bourguignon, Magalie Caubet, Vincent Dewar, Ugo D’Oro, Oretta Finco, Nathalie Garçon, Mohamed El Idrissi, Michel Janssens, Geert Leroux-Roels, Arnaud Marchant, Tino Schwarz, Pierre Van Damme, Gianfranco Volpini, Robbert van der Most, Arnaud M. Didierlaurent, Wivine Burny
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00337-0