Efficacy and safety of twice-daily treatment with canagliflozin, a sodium glucose co-transporter 2 inhibitor, added on to metformin monotherapy in patients with type 2 diabetes mellitus

Aim: To evaluate the efficacy/safety of canagliflozin twice daily (BID) compared with placebo in patients with type 2 diabetes mellitus (T2DM) on metformin. Methods: In this 18-week, randomized, double-blind, placebo-controlled study, patients (N = 279) at 60 centers in 7 countries received canaglif...

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Bibliographic Details
Main Authors: Rong Qiu, MD, PhD, George Capuano, PhD, Gary Meininger, MD
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Journal of Clinical & Translational Endocrinology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214623714000143