Thromboxane A2 mediates cation-induced airway hyperresponsiveness through the bradykinin B2 receptor in guinea pigs

Thromboxane A2 mediates cation-induced airway hyperresponsiveness through the bradykinin B2 receptor in guinea pigs

To elucidate the mechanisms of cationic protein-induced airway hyperresponsiveness (AHR), the airway response to methacholine, and the concentrations of thromboxane B2 (TXB2) and 6-keto-PGF1α in the bronchoalveolar lavage fluid (BALF) of guinea-pigs were measured after inhalation of poly-L-lysine (P...

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Bibliographic Details
Main Authors: Tomohiko Shirotani, Hitoshi Maeda, Yoshihiro Nishimura, Mitsuhiro Yokoyama
Format: Article
Language:English
Published: Elsevier 1999-01-01
Series:Allergology International
Subjects:
airway hyperresponsiveness
bradykinin
cationic protein
low molecular weight heparin
poly- L-lysine
6-keto-PGF1α
thromboxane A2
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015314696

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http://www.sciencedirect.com/science/article/pii/S1323893015314696

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