Prevalence, Risk Factors, and Treatment Outcomes of Isoniazid- and Rifampicin-Mono-Resistant Pulmonary Tuberculosis in Lima, Peru.

BACKGROUND:Isoniazid and rifampicin are the two most efficacious first-line agents for tuberculosis (TB) treatment. We assessed the prevalence of isoniazid and rifampicin mono-resistance, associated risk factors, and the association of mono-resistance on treatment outcomes. METHODS:A prospective, ob...

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Bibliographic Details
Main Authors: Leonela Villegas, Larissa Otero, Timothy R Sterling, Moises A Huaman, Patrick Van der Stuyft, Eduardo Gotuzzo, Carlos Seas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4821555?pdf=render