Block catiomer with flexible cationic segment enhances complexation with siRNA and the delivery performance in vitro
RNA interference (RNAi) by small interfering RNAs (siRNAs) is a promising therapeutic approach. Because siRNA has limited intracellular access and is rapidly cleared in vivo, the success of RNAi depends on efficient delivery technologies. Particularly, polyion complexation between block catiomers an...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2021-09-01
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Series: | Science and Technology of Advanced Materials |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/14686996.2021.1976055 |