Impaired Fear Extinction Recall in Serotonin Transporter Knockout Rats Is Transiently Alleviated during Adolescence

Impaired Fear Extinction Recall in Serotonin Transporter Knockout Rats Is Transiently Alleviated during Adolescence

Adolescence is a developmental phase characterized by emotional turmoil and coincides with the emergence of affective disorders. Inherited serotonin transporter (5-HTT) downregulation in humans increases sensitivity to these disorders. To reveal whether and how <i>5-HTT</i> gene variance...

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Bibliographic Details
Main Authors: Pieter Schipper, Paola Brivio, David de Leest, Leonie Madder, Beenish Asrar, Federica Rebuglio, Michel M. M. Verheij, Tamas Kozicz, Marco A. Riva, Francesca Calabrese, Marloes J. A. G. Henckens, Judith R. Homberg
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Brain Sciences
Subjects:
serotonin transporter
rat
fear extinction
medial prefrontal cortex
NMDA
BDNF
adolescence
age
Online Access:https://www.mdpi.com/2076-3425/9/5/118

Internet

https://www.mdpi.com/2076-3425/9/5/118

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