Extracellular vesicle-associated miR-135b and -135a regulate stemness in Group 4 medulloblastoma cells by targeting angiomotin-like 2

Extracellular vesicle-associated miR-135b and -135a regulate stemness in Group 4 medulloblastoma cells by targeting angiomotin-like 2

Abstract Background Extracellular vesicles (EVs) secreted by tumours, including exosomes, are important factors that regulate cell–cell interactions in oncogenesis. Although EV studies are ongoing, the biological understanding of EV-miRNAs derived from brain tumour spheroid-forming cells (BTSCs) of...

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Bibliographic Details
Main Authors: Seung Ah Choi, Eun Jung Koh, Ryong Nam Kim, Jung Woo Byun, Ji Hoon Phi, Jeyul Yang, Kyu-Chang Wang, Ae Kyung Park, Do Won Hwang, Ji Yeoun Lee, Seung-Ki Kim
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cancer Cell International
Subjects:
Medulloblastoma
Brain tumour spheroid-forming cells
miR-135b
miR-135a
AMOTL2
Online Access:http://link.springer.com/article/10.1186/s12935-020-01645-6

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http://link.springer.com/article/10.1186/s12935-020-01645-6

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