Endothelin-dependent vasoconstriction in human uterine artery: application to preeclampsia.

BACKGROUND: Reduced uteroplacental perfusion, the initiating event in preeclampsia, is associated with enhanced endothelin-1 (ET-1) production which feeds the vasoconstriction of uterine artery. Whether the treatments of preeclampsia were effective on ET-1 induced contraction and could reverse place...

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Bibliographic Details
Main Authors: Clotilde Dechanet, Aurélie Fort, Elisabet Barbero-Camps, Hervé Dechaud, Sylvain Richard, Anne Virsolvy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3027698?pdf=render