Treatment effects between monotherapy of donepezil versus combination with memantine for Alzheimer disease: A meta-analysis.

This is the first meta-analysis to compare the treatment effects and safety of administering donepezil alone versus a combination of memantine and donepezil to treat patients with moderate to severe Alzheimer Disease, particularly regarding cognitive functions, behavioral and psychological symptoms...

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Bibliographic Details
Main Authors: Ruey Chen, Pi-Tuan Chan, Hsin Chu, Yu-Cih Lin, Pi-Chen Chang, Chien-Yu Chen, Kuei-Ru Chou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5565113?pdf=render