CHTOP in Chemoresistant Epithelial Ovarian Cancer: A Novel and Potential Therapeutic Target

CHTOP in Chemoresistant Epithelial Ovarian Cancer: A Novel and Potential Therapeutic Target

Objective: Chemoresistance is a major challenge in epithelial ovarian cancer (EOC) treatment. Chromatin target of protein arginine methyltransferase (CHTOP) was identified as a potential biomarker in chemoresistant EOC cell lines using label-free LC-MS/MS quantitative proteomics. Thus, the aim of th...

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Bibliographic Details
Main Authors: Xiaojie Feng, Xupeng Bai, Jie Ni, Valerie C. Wasinger, Julia Beretov, Ying Zhu, Peter Graham, Yong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer
chemoresistance
CHTOP
apoptosis
stemness
metastasis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00557/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00557/full

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