Comparison of strategies to detect epistasis from eQTL data.

Genome-wide association studies have been instrumental in identifying genetic variants associated with complex traits such as human disease or gene expression phenotypes. It has been proposed that extending existing analysis methods by considering interactions between pairs of loci may uncover addit...

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Bibliographic Details
Main Authors: Karen Kapur, Thierry Schüpbach, Ioannis Xenarios, Zoltán Kutalik, Sven Bergmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3242756?pdf=render