Triple-Gene Therapy for Stroke: A Proof-of-Concept in Vivo Study in Rats

Triple-Gene Therapy for Stroke: A Proof-of-Concept in Vivo Study in Rats

Natural brain repair after stroke is extremely limited, and current therapeutic options are even more scarce with no clinical break-through in sight. Despite restricted regeneration in the central nervous system, we have previously proved that human umbilical cord blood mono-nuclear cells (UCB-MC) t...

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Bibliographic Details
Main Authors: Mikhail E. Sokolov, Farid V. Bashirov, Vage A. Markosyan, Tatyana V. Povysheva, Filip O. Fadeev, Andrey A. Izmailov, Maxim S. Kuztetsov, Zufar Z. Safiullov, Maxim M. Shmarov, Boris S. Naroditskyi, András Palotás, Rustem R. Islamov
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
adenoviral vector
GDNF
gene therapy
human umbilical cord blood mono-nuclear cell
middle cerebral artery
NCAM
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00111/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00111/full

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