The effect of ApoE ε4 on longitudinal brain region-specific glucose metabolism in patients with mild cognitive impairment: a FDG-PET study

While the ApoE ε4 allele is a known risk factor for mild cognitive impairment (MCI) and Alzheimer's disease, brain region specific effects remain elusive. In this study, we investigate whether the ApoE ε4 allele exhibits brain region specific effects in longitudinal glucose uptake among patient...

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Bibliographic Details
Main Authors: Manish D. Paranjpe, Xueqi Chen, Min Liu, Ishan Paranjpe, Jeffrey P. Leal, Rongfu Wang, Martin G. Pomper, Dean F. Wong, Tammie L.S. Benzinger, Yun Zhou
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158219301457