SLIT2 Overexpression in Periodontitis Intensifies Inflammation and Alveolar Bone Loss, Possibly via the Activation of MAPK Pathway

SLIT2 Overexpression in Periodontitis Intensifies Inflammation and Alveolar Bone Loss, Possibly via the Activation of MAPK Pathway

SLIT2, a member of neuronal guidance cues, has been reported to regulate inflammation and cancer progression. Periodontitis is an oral inflammatory disease that degenerates periodontal tissue, alveolar bone and tooth. This study aims to explore the expression pattern of SLIT2 in periodontitis and it...

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Bibliographic Details
Main Authors: Liping Wang, Jing Zheng, Janak L. Pathak, Yunxin Chen, Dongliang Liang, Luxi Yang, Haobo Sun, Mei Zhong, Lihong Wu, Li Li, Shuhua Deng, Lingyun Zheng, Yongyong Yan, Dan Hou, Lijing Wang, Linhu Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SLIT2
periodontitis
alveolar bone loss
osteoclasts
MAPK signaling
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00593/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00593/full

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