Multiple umbilical cord–derived MSCs administrations attenuate rat osteoarthritis progression via preserving articular cartilage superficial layer cells and inhibiting synovitis

Multiple umbilical cord–derived MSCs administrations attenuate rat osteoarthritis progression via preserving articular cartilage superficial layer cells and inhibiting synovitis

Background/objectives: Articular cartilage erosion probably plays a substantial role in osteoarthritis (OA) initiation and development. Studies demonstrated that umbilical cord–derived mesenchymal stem cells (UCMSCs) could delay chondrocytes apoptosis and ameliorate OA progression in patients, but t...

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Bibliographic Details
Main Authors: Wei Tong, Xiaoguang Zhang, Quan Zhang, Jiarui Fang, Yong Liu, Zengwu Shao, Shuhua Yang, Dongcheng Wu, Xiaoming Sheng, Yingze Zhang, Hongtao Tian
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Journal of Orthopaedic Translation
Subjects:
Cartilage superficial layer cells
Chondrocyte
Osteoarthritis
Synovitis
Umbilical cord–derived mesenchymal stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X20300371

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http://www.sciencedirect.com/science/article/pii/S2214031X20300371

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