Sepsis Inflammation Impairs the Generation of Functional Dendritic Cells by Targeting Their Progenitors

Sepsis Inflammation Impairs the Generation of Functional Dendritic Cells by Targeting Their Progenitors

BackgroundSepsis is a complex systemic immune dysfunction syndrome induced by infection. Sepsis has a high mortality rate, with most patients dying due to systemic organ failure or secondary infection. Dendritic cells (DCs) are professional antigen-presenting cells. Upon infection with microbes, DCs...

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Bibliographic Details
Main Authors: Jie Lu, Kun Sun, Huiping Yang, Dan Fan, He Huang, Yi Hong, Shuiyan Wu, HuiTing Zhou, Fang Fang, YanHong Li, Lijun Meng, Jie Huang, Zhenjiang Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
sepsis
dendritic cells
dendritic cell progenitors
common dendritic cell progenitors
G-CSF
IFN-γ
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.732612/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.732612/full

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