Analysis of Single Locus Trajectories for Extracting In Vivo Chromatin Tethering Interactions.

Is it possible to extract tethering forces applied on chromatin from the statistics of a single locus trajectories imaged in vivo? Chromatin fragments interact with many partners such as the nuclear membrane, other chromosomes or nuclear bodies, but the resulting forces cannot be directly measured i...

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Bibliographic Details
Main Authors: Assaf Amitai, Mathias Toulouze, Karine Dubrana, David Holcman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4552938?pdf=render