PKQuest: PBPK modeling of highly lipid soluble and extracellular solutes

One of the primary objectives of physiologically based pharmacokinetics (PBPK) is the prediction of a drug’s pharmacokinetics just from knowledge of its physicochemical structure. Unfortunately, at present, the accuracy of this prediction is limited for most drugs because of uncertainty about the dr...

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Bibliographic Details
Main Author: David G. Levitt
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2019-02-01
Series:ADMET and DMPK
Subjects:
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/579