Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells

Pericytes and vascular smooth muscle cells are crucial for functional blood vessels, but the developmental sources of these cells are incompletely understood. Here, the authors show that endocardial endothelial cells give rise to cardiac mural cells, which are controlled by Wnt signalling.

Bibliographic Details
Main Authors: Qi Chen, Hui Zhang, Yang Liu, Susanne Adams, Hanna Eilken, Martin Stehling, Monica Corada, Elisabetta Dejana, Bin Zhou, Ralf H. Adams
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12422